WB analysis of A549 cells treated with etoposide 25uM (24h) lysate using GTX86957 MMP1 (cleaved Phe100) antibody. The lane on the right is blocked with the synthesized peptide.
WB analysis of A549 cells treated with etoposide 25uM (24h) lysate using GTX86957 MMP1 (cleaved Phe100) antibody. The lane on the right is blocked with the synthesized peptide.
MMP1 (cleaved Phe100) antibody
GTX86957
Overview
- SupplierGeneTex
- Product NameMMP1 (cleaved Phe100) antibody
- Delivery Days Customer9
- Antibody SpecificityMMP1 (cleaved Phe100) antibody detects endogenous levels of fragment of activated MMP1 resulting from cleavage adjacent to Phe100.
- Application Supplier NoteWB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4312
- Target nameMMP1
- Target descriptionmatrix metallopeptidase 1
- Target synonymsCLG; CLGN; fibroblast collagenase; interstitial collagenase; matrix metallopeptidase 1 (interstitial collagenase); matrix metalloprotease 1
- HostRabbit
- IsotypeIgG
- Protein IDP03956
- Protein NameInterstitial collagenase
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203