MMP12 antibody [7G20]

GeneTex

MMP12 antibody [7G20]

9

This antibody recognizes human MMP-12 in western blot without cross reactivity with other human MMPs.

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:300. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

7G20

200 ug/ml

Unconjugated

MMP12

matrix metallopeptidase 12

HME; macrophage metalloelastase; matrix metallopeptidase 12 (macrophage elastase); matrix metalloproteinase 12 (macrophage elastase); ME; MME; MMP-12

Mouse

IgG2

Macrophage metalloelastase

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203