MMP3 antibody [3E44]

GeneTex

MMP3 antibody [3E44]

9

This antibody recognizes human MMP-3 in western blot without cross reactivity with other human MMPs.

WB: 1:500 - 1:1000. IHC-P: 1:200 - 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

200 ug/ml

Unconjugated

MMP3

matrix metallopeptidase 3

CHDS6; matrix metalloproteinase 3 (stromelysin 1, progelatinase); MMP-3; proteoglycanase; SL-1; STMY; STMY1; STR1; stromelysin-1; transin-1

Mouse

IgG1

Stromelysin-1

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203