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MMP3 antibody [N3C1], Internal

GTX100723
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMMP3
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Overview

  • Supplier
    GeneTex
  • Product Name
    MMP3 antibody [N3C1], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4314
  • Target name
    MMP3
  • Target description
    matrix metallopeptidase 3
  • Target synonyms
    CHDS6; matrix metalloproteinase 3 (stromelysin 1, progelatinase); MMP-3; proteoglycanase; SL-1; STMY; STMY1; STR1; stromelysin-1; transin-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08254
  • Protein Name
    Stromelysin-1
  • Scientific Description
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.
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  • PKCdelta mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression. Mandal JP et al., 2021 Feb 1, Free Radic Biol Med
    Read more
  • Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. Huang HY et al., 2020 Sep, J Cell Mol Med
    Read more
  • Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol Lett
    Read more
  • Upregulation of LGALS1 is associated with oral cancer metastasis. Li JM et al., 2018, Ther Adv Med Oncol
    Read more
  • Senescent tumor cells lead the collective invasion in thyroid cancer. Kim YH et al., 2017 May 10, Nat Commun
    Read more
  • Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs. Bu S et al., 2014 Dec 15, Arch Biochem Biophys
    Read more