MMP3 antibody [N3C1], Internal
GTX100723
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMMP3
Overview
- SupplierGeneTex
- Product NameMMP3 antibody [N3C1], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4314
- Target nameMMP3
- Target descriptionmatrix metallopeptidase 3
- Target synonymsCHDS6; matrix metalloproteinase 3 (stromelysin 1, progelatinase); MMP-3; proteoglycanase; SL-1; STMY; STMY1; STR1; stromelysin-1; transin-1
- HostRabbit
- IsotypeIgG
- Protein IDP08254
- Protein NameStromelysin-1
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.Read more
- PKCdelta mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression. Mandal JP et al., 2021 Feb 1, Free Radic Biol MedRead more
- Progesterone receptor membrane component 1 is involved in oral cancer cell metastasis. Huang HY et al., 2020 Sep, J Cell Mol MedRead more
- Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol LettRead more
- Upregulation of LGALS1 is associated with oral cancer metastasis. Li JM et al., 2018, Ther Adv Med OncolRead more
- Senescent tumor cells lead the collective invasion in thyroid cancer. Kim YH et al., 2017 May 10, Nat CommunRead more
- Simulated physiological stretch-induced proliferation of human bladder smooth muscle cells is regulated by MMPs. Bu S et al., 2014 Dec 15, Arch Biochem BiophysRead more