MnTBAP chloride [55266-18-7]

AdipoGen Life Sciences

MnTBAP chloride

10

55266-18-7

Research Use Only

>97%

C48H28MnN4O8Cl

879.2

Cell permeable superoxide dismutase (SOD) mimetic [1, 2]. Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO) [3]. Neuronal apoptosis inhibitor [4]. Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death [5]. Lipopolysaccharide-induced TNF-alpha production inhibitor, by prevention of intracellular ROS generation and subsequent inactivation of p38 MAPK and SAPK/JNK [6]. . - Chemical. CAS: 55266-18-7. Formula: C48H28MnN4O8Cl. MW: 879.2. Cell permeable superoxide dismutase (SOD) mimetic. Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO). Neuronal apoptosis inhibitor. Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death. Lipopolysaccharide-induced TNF-alpha production inhibitor, by prevention of intracellular ROS generation and subsequent inactivation of p38 MAPK and SAPK/JNK. .

[Cl-].OC(=O)C1=CC=C(C=C1)C1=C2C=CC3=C(C4C=CC5=C(C6=CC=C7N6[Mn+3](N6C1C=CC6=C7C1=CC=C(C=C1)C(O)=O)(N45)N23)C1=CC=C(C=C1)C(O)=O)C1=CC=C(C=C1)C(O)=O

-20°C,2°C to 8°C

12352200