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Monoamine Oxidase B antibody [N2C3]

Name: Monoamine Oxidase B antibody [N2C3]
SKU: GTX105970_G10
Availability: BackOrder

GTX105970

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman, Mouse

TargetMAOB

Overview

Supplier
GeneTex
Product Name
Monoamine Oxidase B antibody [N2C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.51 mg/ml
Conjugate
Unconjugated
Gene ID4129
Target name
MAOB
Target description
monoamine oxidase B
Target synonyms
amine oxidase [flavin-containing] B, MAO, brain, MAO, platelet, MAO-B, adrenalin oxidase, monoamine oxidase type B, tyramine oxidase
Host
Rabbit
Isotype
IgG
Protein IDP27338
Protein Name
Amine oxidase [flavin-containing] B
Scientific Description
The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Chen PH, Wang YY, Lan TH, et al. Genetic and Proteinic Linkage of MAO and COMT with Oral Potentially Malignant Disorders and Cancers of the Oral Cavity and Pharynx. Cancers (Basel). 2021,13(13). doi: 10.3390/cancers13133268
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Yang YC, Chien MH, Lai TC, et al. Monoamine Oxidase B Expression Correlates with a Poor Prognosis in Colorectal Cancer Patients and Is Significantly Associated with Epithelial-to-Mesenchymal Transition-Related Gene Signatures. Int J Mol Sci. 2020,21(8). doi: 10.3390/ijms21082813
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Liu Y, Feng S, Subedi K, et al. Attenuation of Ischemic Stroke-Caused Brain Injury by a Monoamine Oxidase Inhibitor Involves Improved Proteostasis and Reduced Neuroinflammation. Mol Neurobiol. 2020,57(2):937-948. doi: 10.1007/s12035-019-01788-2
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Kang SS, Ahn EH, Zhang Z, et al. α-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease. EMBO J. 2018,37(12). doi: 10.15252/embj.201798878
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