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Motesanib

M5329
AbMole BioScience
CAS Number453562-69-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>99.0%
Molecular Weight373.45
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Motesanib
  • Delivery Days Customer
    9
  • CAS Number
    453562-69-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99.0%
  • Molecular Formula
    C22H23N5O
  • Molecular Weight
    373.45
  • Scientific Description
    Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 2 nM/3 nM/6 nM, respectively; similar activity against Kit, ~10-fold more selective for VEGFR than PDGFR and Ret.
  • SMILES
    CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3
  • UNSPSC
    12352200

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