Mouse anti Human Caspase-6
X1173M
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCASP6
Overview
- SupplierNordic-MUbio
- Product NameMouse anti Human Caspase-6
- Delivery Days Customer7
- Application Supplier NoteDetects proenzyme form of human Caspase-6 by Western blot. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMCH2 14 1-190
- ConjugateUnconjugated
- Gene ID839
- Target nameCASP6
- Target descriptioncaspase 6
- Target synonymsapoptotic protease MCH-2; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; MCH2
- HostMouse
- IsotypeIgG
- Protein IDP55212
- Protein NameCaspase-6
- Scientific DescriptionCysteine-requiring Aspartate Protease-6; Apoptotic protease Mch-2
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteHybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-6 protein and mouse myeloma cells.
- UNSPSC12352203
References
- 1. Kidd, V.J., Proteolytic activities that mediate apoptosis. Annu. Rev. Physiol. 1998, 60, 533-573 2. Fernandes – Alnemri, T., et al., Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. Cancer Res. 1995, 55, 2737-2742 3. Orth, K., et al., The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A. J. Biol. Chem. 1996, 271, 16443 4. Hirata, H., et al., Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J. Exp. Med. 1998, 187, 587-600 5. Slee, E. A., et al., Ordering the cytochrome c-initiated caspase cascade: hierarchial activation of caspases-2, -3, -6, -7, -8 and -10 in a caspase-9-dependent manner. J. Cell Biol., 144, 281 (1999) 6. Cohen, G.M., et al. Caspases: the executioners of apoptosis. Biochem. J. 1997, 326, 1-16