Mouse anti Human LEF-1 transactivation domain
X1074M
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetLEF1
Overview
- SupplierNordic-MUbio
- Product NameMouse anti Human LEF-1 transactivation domain
- Delivery Days Customer7
- Application Supplier NoteAntibody detects amino acids 236-242 of human LEF-1. Epitope is missing in some splice variants. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3A12
- ConjugateUnconjugated
- Gene ID51176
- Target nameLEF1
- Target descriptionlymphoid enhancer binding factor 1
- Target synonymsLEF-1; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
- HostMouse
- IsotypeIgG1
- Protein IDQ9UJU2
- Protein NameLymphoid enhancer-binding factor 1
- Scientific DescriptionAnti-Lymphoid Enhancer Factor-1, Transactivation Domain (amino acids 236-242) Monoclonal Antibody
- Shelf life instructionSee expiration date on vial
- SourceHybridoma produced by the fusion of splenocytes from mice immunized with synthetic peptide corresponding to amino acids 236-242 of human LEF-1 and mouse myeloma cells
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier Note.
- UNSPSC12352203
References
- 1. Riese, J., et al., LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell 1997, 88, 777-787 2. Giese, K., et al. Functional analysis of DNA bending and unwinding by the high mobility group domain of LEF-1. Proc. Natl. Acad. Sci. USA 1997, 94, 12845-12850 3. Behrens, J., et al. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996, 382, 638-642 4. Giese, K. and Grosschedl, R. LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites. EMBO J. 1993, 12, 4667-4676