Mouse IL12 p70 ELISA Kit

Arigo Biolaboratories

Mouse IL12 p70 ELISA Kit

23

ELISA

CV:

8 pg/ml

No significant cross-reactivity or interference with Mouse IL-12 p35, IL-12/IL-23 p40 monomer, IL-12/IL-23 p40 dimer, IL-23; human IL-12 p70, IL-12 p35, IL-12/IL-23 p40 monomer; canine IL-12 p70; feline IL-12 p70

4 hours

Research Use Only

Interleukin-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23. Additionally, p40 can associate itself through disulfide linkage to form a dimer that acts as a potent IL12 antagonist. Recombinant murine IL-12 p40 is a 40.0 kDa protein containing 313 amino acid residues.

2°C to 8°C

41116133