Western blot analysis of extracts of various cell lines using MRPL12 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using MRPL12 Polyclonal Antibody at 1:1000 dilution.
MRPL12 Polyclonal Antibody
E-AB-62899
Product group Antibodies
Overview
- SupplierElabscience
- Product NameMRPL12 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.
- UNSPSC12352203