Bio-Connect

MRTX-1257

HY-114436
MedChem Express
CAS Number2206736-04-9
Product group Chemicals
Estimated Purity99.14
Molecular Weight565.71
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Overview

  • Supplier
    MedChem Express
  • Product Name
    MRTX-1257 [2206736-04-9]
  • Delivery Days Customer
    10
  • CAS Number
    2206736-04-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.14
  • Molecular Formula
    C33H39N7O2
  • Molecular Weight
    565.71
  • Scientific Description
    MRTX-1257 is a selective, irreversible, covalent and orally active KRAS G12C inhibitor, with an IC 50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells [1] .
  • SMILES
    N#CC[C@@H]1N(C(C=C)=O)CCN(C2=C3C(CN(C4=C5C(C)=CC=CC5=CC=C4)CC3)=NC(OC[C@H]6N(C)CCC6)=N2)C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200