MS1943

AbMole BioScience

MS1943

9

2225938-17-8

Chemical

Research Use Only

C42H54N8O3

718.93

MS1943 is a pioneering oral bioactive selective EZH2 inhibitor with an IC50 of 120 nM. MS1943 significantly reduced EZH2 protein levels in many triple negative breast and other cancers and non-cancer lines. MS1943 effectively blocked the proliferation of multiple triple negative breast cancers and other cancer lines.

CC(C)[N]1N=CC2=C1C=C(C=C2C(=O)NCC3=C(C)C=C(C)NC3=O)C4=CN=C(C=C4)N5CCN(CCNC(=O)CC67CC8CC(CC(C8)C6)C7)CC5

12352200