MS4078
S0072
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameMS4078
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionMS4078 is an inhibitor and PROTAC (degrader) of ALK. MS4078 reduces the NPM-ALK protein levels in SU-DHL-1 cells and the EML4-ALK protein levels in NCI-H2228 cells with DC50 of 11 nM and 59 nM, respectively. MS4078 induces ALK protein degradation via cereblon and proteasome dependent mechanism and potently inhibits proliferation of SU-DHL-1 cells with IC50 of 33 nM.
- UNSPSC12352200
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