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MSL2 Antibody, Biotin conjugated

CSB-PA875722LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetMSL2
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Overview

  • Supplier
    Cusabio
  • Product Name
    MSL2 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID55167
  • Target name
    MSL2
  • Target description
    MSL complex subunit 2
  • Target synonyms
    E3 ubiquitin-protein ligase MSL2; E3 ubiquitin-protein transferase MSL2; male-specific lethal 2 homolog; male-specific lethal 2-like 1; male-specific lethal-2 homolog 1; MSL-2; MSL2L1; MSL2-like 1; ring finger protein 184; RNF184
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9HCI7
  • Protein Name
    E3 ubiquitin-protein ligase MSL2
  • Scientific Description
    Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at Lys-35 (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at Lys-4 (H3K4me) and Lys-79 (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203