MTI-31 [1567915-38-1]

TargetMol Chemicals

MTI-31 [1567915-38-1]

4

1567915-38-1

Chemical

Research Use Only

MTI-31

99.76%

C26H30N6O3

474.55

MTI-31 (LXI-15029) is a potent, orally active, and highly selective inhibitor of mTORC1 and mTORC2, exhibiting a Kd of 0.20 nM for mTOR and >5,000-fold selectivity over PIK3CA, PIK3CB, and PIK3G in binding assays, with an IC50 of 39 nM for mTOR in a LANCE assay of mTOR substrate phosphorylation with 100 microM ATP [1].

3 years

CNC(=O)c1cccc(c1)-c1ccc2c(nc(nc2n1)N1CCOC[C@@H]1C)N1C2CCC1COC2

-20°C

12352200