MUC18 / Mucin 18 / CD146(OJ79c), Biotin conjugate, 0.1mg/mL [26628-22-8]

Biotium

MUC18 / Mucin 18 / CD146(OJ79c), Biotin conjugate, 0.1mg/mL

9

Flow Cytometry, ImmunoFluorescence, ELISA

Research Use Only

Monoclonal

OJ79c

0.1 mg/ml

Biotin

MCAM

melanoma cell adhesion molecule

CD146; cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; melanoma adhesion molecule; melanoma-associated antigen A32; melanoma-associated antigen MUC18; MelCAM; METCAM; MUC18; S-endo 1 endothelial-associated antigen

Mouse

IgG1

Cell surface glycoprotein MUC18

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2 -independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203