MUC2 antibody [C3], C-term
GTX100664
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMUC2
Overview
- SupplierGeneTex
- Product NameMUC2 antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.9 mg/ml
- ConjugateUnconjugated
- Gene ID4583
- Target nameMUC2
- Target descriptionmucin 2, oligomeric mucus/gel-forming
- Target synonymsMLP, MUC-2, SMUC, mucin-2, mucin 2, intestinal/tracheal
- HostRabbit
- IsotypeIgG
- Protein IDQ02817
- Protein NameMucin-2
- Scientific DescriptionThis gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yang WH, Aziz PV, Heithoff DM, et al. Innate mechanism of mucosal barrier erosion in the pathogenesis of acquired colitis. iScience. 2023,26(10):107883. doi: 10.1016/j.isci.2023.107883Read this paper
- Duan C, Wu J, Wang Z, et al. Fucose promotes intestinal stem cell-mediated intestinal epithelial development through promoting Akkermansia-related propanoate metabolism. Gut Microbes. 2023,15(1):2233149. doi: 10.1080/19490976.2023.2233149Read this paper
- Han Y, Ling Q, Wu L, et al. Akkermansia muciniphila inhibits nonalcoholic steatohepatitis by orchestrating TLR2-activated γδT17 cell and macrophage polarization. Gut Microbes. 2023,15(1):2221485. doi: 10.1080/19490976.2023.2221485Read this paper
- Cortez V, Livingston B, Sharp B, et al. Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection. Mucosal Immunol. 2023,16(4):551-562. doi: 10.1016/j.mucimm.2023.05.011Read this paper
- Canale V, Spalinger MR, Alvarez R, et al. PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice. Cell Mol Gastroenterol Hepatol. 2023,16(1):39-62. doi: 10.1016/j.jcmgh.2023.03.009Read this paper
- He Q, Guo K, Wang L, et al. Tannins amount determines whether tannase-containing bacteria are probiotic or pathogenic in IBD. Life Sci Alliance. 2023,6(5). doi: 10.26508/lsa.202201702Read this paper
- Wang Z, Tan C, Duan C, et al. FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response. Redox Biol. 2023,60:102618. doi: 10.1016/j.redox.2023.102618Read this paper
- Lin SJ, Helm ET, Gabler NK, et al. Acute infection with Brachyspira hyodysenteriae affects mucin expression, glycosylation, and fecal MUC5AC. Front Cell Infect Microbiol. 2022,12:1042815. doi: 10.3389/fcimb.2022.1042815Read this paper
- Xu Y, Xiong Y, Liu Y, et al. Activation of goblet cell Piezo1 alleviates mucus barrier damage in mice exposed to WAS by inhibiting H3K9me3 modification. Cell Biosci. 2023,13(1):7. doi: 10.1186/s13578-023-00952-5Read this paper
- Liu Y, Fang F, Xiong Y, et al. Reprogrammed fecal and mucosa-associated intestinal microbiota and weakened mucus layer in intestinal goblet cell- specific Piezo1-deficient mice. Front Cell Infect Microbiol. 2022,12:1035386. doi: 10.3389/fcimb.2022.1035386Read this paper
Datasheet
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