MUC2 antibody [C3], C-term
GTX100664
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Rat
TargetMUC2
Overview
- SupplierGeneTex
- Product NameMUC2 antibody [C3], C-term
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4583
- Target nameMUC2
- Target descriptionmucin 2, oligomeric mucus/gel-forming
- Target synonymsMLP; MUC-2; mucin 2, intestinal/tracheal; mucin-2; SMUC
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]
- ReactivityHuman, Mouse, Porcine, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- The disulfide catalyst QSOX1 maintains the colon mucosal barrier by regulating Golgi glycosyltransferases. Ilani T et al., 2023 Jan 16, EMBO JRead more
- Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer. Sharpen JDA et al., 2022 Jan 11, Nat CommunRead more
- An Active Fraction of Trillium tschonoskii Promotes the Regeneration of Intestinal Epithelial Cells After Irradiation. Song F et al., 2021, Front Cell Dev BiolRead more
- Identification and characterization of a novel Enterococcus bacteriophage with potential to ameliorate murine colitis. Nishio J et al., 2021 Oct 12, Sci RepRead more
- Role for Mucin-5AC in Upper and Lower Airway Pathogenesis in Mice. Cho HY et al., 2021 Jul, Toxicol PatholRead more
- RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways. Gudino V et al., 2021 Apr 20, Nat CommunRead more
- IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during weaning. Layunta E et al., 2021 Feb 16, Cell RepRead more
- Novel FXR agonist nelumal A suppresses colitis and inflammation-related colorectal carcinogenesis. Miyazaki T et al., 2021 Jan 12, Sci RepRead more
- Effects of different doses lipopolysaccharides on the mucosal barrier in mouse intestine. Li C et al., 2020 Dec, Res Vet SciRead more
- Me6TREN targets beta-catenin signaling to stimulate intestinal stem cell regeneration after radiation. Wang S et al., 2020, TheranosticsRead more