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Mucin 5AC antibody [45M1]

Name: Mucin 5AC antibody [45M1]
SKU: GTX11335_G10
Availability: BackOrder

GTX11335

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetMUC5AC

Overview

Supplier
GeneTex
Product Name
Mucin 5AC antibody [45M1]
Delivery Days Customer
7
Application Supplier Note
IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
45M1
Conjugate
Unconjugated
Gene ID4586
Target name
MUC5AC
Target description
mucin 5AC, oligomeric mucus/gel-forming
Target synonyms
MUC5, TBM, leB, mucin, mucin-5AC, gastric mucin, lewis B blood group antigen, major airway glycoprotein, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, tracheobronchial mucin
Host
Mouse
Isotype
IgG1
Protein IDP98088
Protein Name
Mucin-5AC
Scientific Description
Mucin is a high M.W. (>1,000 kDa) glycoprotein, expressed by mucus cells of the gastric epithelium and by goblet cells of the fetal, precancerous and cancerous colon, but not by those of the normal colon. It also appears in other epithelial tissues, which are embryologically derived from the foregut (epigastric and bronchial epithelium) and in Muller ducts (mucus cells of the endocervix and urethral epithelium near the prostatic utriculus).
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Hu CM, Huang CC, Hsu MF, et al. Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation. Adv Sci (Weinh). 2023,10(36):e2301240. doi: 10.1002/advs.202301240
Read this paper
Xue Y, Bao W, Zhou Y, et al. Small-Airway Dysfunction is Involved in the Pathogenesis of Asthma: Evidence from Two Mouse Models. J Asthma Allergy. 2021,14:883-896. doi: 10.2147/JAA.S312361
Read this paper
Yang DQ, Zuo QN, Wang T, et al. Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke. Oxid Med Cell Longev. 2021,2021:6644238. doi: 10.1155/2021/6644238
Read this paper
Yang Z, Sun H, Su S, et al. Tsantan Sumtang Restored Right Ventricular Function in Chronic Hypoxia-Induced Pulmonary Hypertension Rats. Front Pharmacol. 2020,11:607384. doi: 10.3389/fphar.2020.607384
Read this paper
Yang D, Xu D, Wang T, et al. Mitoquinone ameliorates cigarette smoke-induced airway inflammation and mucus hypersecretion in mice. Int Immunopharmacol. 2021,90:107149. doi: 10.1016/j.intimp.2020.107149
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Tamura M, Tanaka T, Fujii N, et al. Potential Interaction between Galectin-2 and MUC5AC in Mouse Gastric Mucus. Biol Pharm Bull. 2020,43(2):356-360. doi: 10.1248/bpb.b19-00705
Read this paper
Nagaoka K, Ogino K, Ogino N, et al. Human albumin augmented airway inflammation induced by PM2.5 in NC/Nga mice. Environ Toxicol. 2019,34(7):836-843. doi: 10.1002/tox.22751
Read this paper
Jing L, Su S, Zhang D, et al. Srolo Bzhtang, a traditional Tibetan medicine formula, inhibits cigarette smoke induced airway inflammation and muc5ac hypersecretion via suppressing IL-13/STAT6 signaling pathway in rats. J Ethnopharmacol. 2019,235:424-434. doi: 10.1016/j.jep.2019.02.006
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Mucin 5AC antibody [45M1]

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