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ProductsBack/Mucin 5AC antibody [45M1]

Mucin 5AC antibody [45M1]

GTX11335
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityChicken, Feline, Hedgehog, Human, Monkey, Mouse, Porcine, Rabbit, Rat
TargetMUC5AC
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Overview

  • Supplier
    GeneTex
  • Product Name
    Mucin 5AC antibody [45M1]
  • Delivery Days Customer
    7
  • Antibody Specificity
    The antibody recognizes the mucin epitope g located in the peptide core of gastric mucin (>1,000 kDa). This epitope is completely destroyed by thiol reduction (using mercaptoethanol) and partially lost following trypsin proteolysis, but is stable upon
  • Application Supplier Note
    IHC-P: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    45M1
  • Conjugate
    Unconjugated
  • Gene ID4586
  • Target name
    MUC5AC
  • Target description
    mucin 5AC, oligomeric mucus/gel-forming
  • Target synonyms
    gastric mucin; leB; lewis B blood group antigen; major airway glycoprotein; MUC5; mucin; mucin 5, subtypes A and C, tracheobronchial/gastric; mucin 5AC, oligomeric mucus/gel-forming pseudogene; mucin-5 subtype AC, tracheobronchial; mucin-5AC; TBM; tracheobronchial mucin
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP98088
  • Protein Name
    Mucin-5AC
  • Scientific Description
    Mucin is a high M.W. (>1,000 kDa) glycoprotein, expressed by mucus cells of the gastric epithelium and by goblet cells of the fetal, precancerous and cancerous colon, but not by those of the normal colon. It also appears in other epithelial tissues, which are embryologically derived from the foregut (epigastric and bronchial epithelium) and in Muller ducts (mucus cells of the endocervix and urethral epithelium near the prostatic utriculus).
  • Reactivity
    Chicken, Feline, Hedgehog, Human, Monkey, Mouse, Porcine, Rabbit, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Oncogenic KRAS, Mucin 4, and Activin A-Mediated Fibroblast Activation Cooperate for PanIN Initiation.
    Read more
  • Small-Airway Dysfunction is Involved in the Pathogenesis of Asthma: Evidence from Two Mouse Models. Xue Y et al., 2021, J Asthma Allergy
    Read more
  • Mitochondrial-Targeting Antioxidant SS-31 Suppresses Airway Inflammation and Oxidative Stress Induced by Cigarette Smoke. Yang DQ et al., 2021, Oxid Med Cell Longev
    Read more
  • Tsantan Sumtang Restored Right Ventricular Function in Chronic Hypoxia-Induced Pulmonary Hypertension Rats. Yang Z et al., 2020, Front Pharmacol
    Read more
  • Mitoquinone ameliorates cigarette smoke-induced airway inflammation and mucus hypersecretion in mice. Yang D et al., 2021 Jan, Int Immunopharmacol
    Read more
  • Potential Interaction between Galectin-2 and MUC5AC in Mouse Gastric Mucus.
    Read more
  • Human albumin augmented airway inflammation induced by PM2.5 in NC/Nga mice. Nagaoka K et al., 2019 Jul, Environ Toxicol
    Read more
  • Srolo Bzhtang, a traditional Tibetan medicine formula, inhibits cigarette smoke induced airway inflammation and muc5ac hypersecretion via suppressing IL-13/STAT6 signaling pathway in rats. Jing L et al., 2019 May 10, J Ethnopharmacol
    Read more