MutL Protein Homolog 1(MLH1) Monoclonal Antibody
RD6124
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMLH1
Overview
- SupplierReddot Biotech
- Product NameMutL Protein Homolog 1(MLH1) Monoclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- Concentration100 ug/ml
- Gene ID4292
- Target nameMLH1
- Target descriptionmutL homolog 1
- Target synonymsCOCA2; DNA mismatch repair protein Mlh1; FCC2; hMLH1; HNPCC; HNPCC2; MMRCS1; mutL homolog 1, colon cancer, nonpolyposis type 2
- HostMouse
- Scientific DescriptionMutL Protein Homolog 1(MLH1) is a mismatch repair gene, which is located on p-arm 21.3 of chromosome 3. And DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite reproducibility is caused by the slippage of the hinge misalignment during DNA replication, also known as microsatellite instability. The defects of these DNA repair pathways are related to some human tumors. The mutant mismatch repair gene is often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant genetic diseases.
- UNSPSC12352203