MW-150 hydrochloride [1923773-01-6]

MedChem Express

MW-150 hydrochloride [1923773-01-6]

10

1923773-01-6

Research Use Only

C24H24ClN5

417.93

MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a selective, CNS penetrant, and orally active inhibitor of p38alpha MAPK with a Ki of 101 nM. MW-150 hydrochloride (MW01-18-150SRM hydrochloride) inhibits the ability of the endogenous p38alpha MAPK to phosphorylate an endogenous substrate MK2 in activated glia[1].

CN1CCN(C2=NN=C(C3=CC=C4C=CC=CC4=C3)C(C5=CC=NC=C5)=C2)CC1.[H]Cl

12352200