MW-150 hydrochloride [1923773-01-6]

TargetMol Chemicals

MW-150 hydrochloride [1923773-01-6]

999

1923773-01-6

Research Use Only

MW-150 hydrochloride

C24H24ClN5

417.94

MW-150 hydrochloride (MW01-18-150SRM hydrochloride) is a potent and selective inhibitor of p38alpha MAPK with a Ki value of 101 nM. It exhibits excellent CNS penetration and oral bioavailability, and effectively suppresses the phosphorylation of MK2, a substrate of endogenous p38alpha MAPK, in activated glial cells.

3 years

Cl.CN1CCN(CC1)c1cc(-c2ccncc2)c(nn1)-c1ccc2ccccc2c1

-20°C

12352200