MYBPC3 antibody

GeneTex

MYBPC3 antibody

9

WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

MYBPC3

myosin binding protein C3

CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C; myosin binding protein C, cardiac; myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C

Rabbit

IgG

Myosin-binding protein C, cardiac-type

MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203