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MYH9 antibody [N1-2], N-term

GTX113236
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMYH9
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Overview

  • Supplier
    GeneTex
  • Product Name
    MYH9 antibody [N1-2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.7 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4627
  • Target name
    MYH9
  • Target description
    myosin heavy chain 9
  • Target synonyms
    BDPLT6; cellular myosin heavy chain, type A; DFNA17; EPSTS; FTNS; MATINS; MHA; myosin, heavy chain 9, non-muscle; myosin-9; NMHC-II-A; NMMHCA; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35579
  • Protein Name
    Myosin-9
  • Scientific Description
    This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Akt1-associated actomyosin remodelling is required for nuclear lamina dispersal and nuclear shrinkage in epidermal terminal differentiation. Rogerson C et al., 2021 Jun, Cell Death Differ
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  • Cisplatin-Mediated Upregulation of APE2 Binding to MYH9 Provokes Mitochondrial Fragmentation and Acute Kidney Injury. Hu Y et al., 2021 Feb 1, Cancer Res
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  • Centrosome guides spatial activation of Rac to control cell polarization and directed cell migration. Cheng HW et al., 2019 Feb, Life Sci Alliance
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  • Comparative proteomic analysis of mouse models of pathological and physiological cardiac hypertrophy, with selection of biomarkers of pathological hypertrophy by integrative Proteogenomics. Kwon HK et al., 2018 Jul 23, Biochim Biophys Acta Proteins Proteom
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  • The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. Li T et al., 2016 Jun 22, Elife
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  • Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow. Sundvold H et al., 2016, Cell Cycle
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  • Mass Spectrometry-Based Proteomics Identification of Enteropathogenic Escherichia coli Pedestal Constituents. Law HT et al., 2015 Jun 5, J Proteome Res
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