
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA884628LA01HU at dilution of 1:100
MYO10 Antibody
CSB-PA884628LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMYO10
Overview
- SupplierCusabio
- Product NameMYO10 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4651
- Target nameMYO10
- Target descriptionmyosin X
- Target synonymsunconventional myosin-10; unconventional myosin-X; unconventionnal myosin-X
- HostRabbit
- IsotypeIgG
- Protein IDQ9HD67
- Protein NameUnconventional myosin-X
- Scientific DescriptionMyosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. In hippocampal neurons it induces the formation of dendritic filopodia by trafficking the actin-remodeling protein VASP to the tips of filopodia, where it promotes actin elongation. Plays a role in formation of the podosome belt in osteoclasts.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161