N-RAS antibody

GeneTex

N-RAS antibody

9

WB: 1 - 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

NRAS

NRAS proto-oncogene, GTPase

ALPS4; CMNS; GTPase NRas; NCMS; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; N-ras; N-ras protein part 4; NRAS1; NS6; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog

Rabbit

IgG

GTPase NRas

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

-20°C or -80°C,2°C to 8°C

12352203