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ProductsBack/NANOS2 Antibody

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA015437LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA015437LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA015437LA01HU at dilution of 1:100

NANOS2 Antibody

CSB-PA015437LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetNANOS2

Overview

Supplier
Cusabio
Product Name
NANOS2 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID339345
Target name
NANOS2
Target description
nanos C2HC-type zinc finger 2
Target synonyms
NOS2, ZC2HC12B, nanos homolog 2, NOS-2
Host
Rabbit
Isotype
IgG
Protein IDP60321
Protein Name
Nanos homolog 2
Scientific Description
Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate. Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate. Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased. Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis. Required for the maintenance of the spermatogonial stem cell population. Not essential for the assembly of P-bodies but is required for the maintenance of their normal state.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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