Navacaprant
HY-124754
CAS Number2244614-14-8
Product group Chemicals
Estimated Purity99.97
Molecular Weight453.562
Overview
- SupplierMedChem Express
- Product NameNavacaprant [2244614-14-8]
- Delivery Days Customer10
- CAS Number2244614-14-8
- Estimated Purity99.97
- Molecular FormulaC25H32FN5O2
- Molecular Weight453.562
- Scientific DescriptionNavacaprant (BTRX-335140) is a selective and orally active kappa opioid receptor (KOR) antagonist, has antagonist activity for kappaOR, microOR and deltaOR with IC 50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats. Navacaprant distributes well into the CNS and can be used for the research of neuropathy [1] .
- SMILESCC1=NOC(C2=C(C)C3=CC(CC)=CC(F)=C3N=C2N4CCC(NC5CCOCC5)CC4)=N1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200