Navarixin [473727-83-2]

MedChem Express

Navarixin [473727-83-2]

5

473727-83-2

Research Use Only

98.90

C21H23N3O5

397.42

Navarixin (SCH 527123) is a potent, allosteric and orally active antagonist of both CXCR1 and CXCR2, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectivelly[1][2].

O=C1C(C(NC2=CC=CC(C(N(C)C)=O)=C2O)=C1N[C@H](CC)C3=CC=C(O3)C)=O

-20°C,2°C to 8°C

12352200