Navarixin

MedChem Express

Navarixin [473727-83-2]

5

473727-83-2

Research Use Only

98.90

C21H23N3O5

397.42

Navarixin (SCH 527123) is a potent, allosteric and orally active antagonist of both CXCR1 and CXCR2 , with K d values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse , rat and cynomolgus monkey CXCR2 , respectivelly [1] [2] .

O=C1C(C(NC2=CC=CC(C(N(C)C)=O)=C2O)=C1N[C@H](CC)C3=CC=C(O3)C)=O

-20°C,2°C to 8°C

12352200