Navarixin

AbMole BioScience

SCH527123

9

473727-83-2

Chemical

Research Use Only

0.9988

C21H23N3O5

397.42

Navarixin (SCH 527123) is a novel, selective CXCR2 receptor antagonist with IC50 of 3 nM. Navarixin (SCH 527123) has Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectivelly.

CCC(NC1=C(NC2=C(O)C(=CC=C2)C(=O)N(C)C)C(=O)C1=O)C3=CC=C(C)O3

12352200