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NDUFS3 antibody

GTX105835
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetNDUFS3
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Overview

  • Supplier
    GeneTex
  • Product Name
    NDUFS3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.31 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4722
  • Target name
    NDUFS3
  • Target description
    NADH:ubiquinone oxidoreductase core subunit S3
  • Target synonyms
    CI-30, MC1DN8, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial, CI-30kD, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase), NADH dehydrogenase-ubiquinone 30 kDa subunit, NADH-ubiquinone oxidoreductase 30 kDa subunit, complex I 30kDa subunit, complex I-30kD
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO75489
  • Protein Name
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
  • Scientific Description
    This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chen KC, Chen CR, Chen CY, et al. Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics. J Clin Med. 2021,11(1). doi: 10.3390/jcm11010135
    Read this paper
  • Thandapani P, Kloetgen A, Witkowski MT, et al. Valine tRNA levels and availability regulate complex I assembly in leukaemia. Nature. 2022,601(7893):428-433. doi: 10.1038/s41586-021-04244-1
    Read this paper
  • Qiao A, Jin X, Pang J, et al. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017,216(3):723-741. doi: 10.1083/jcb.201607091
    Read this paper