NDUFS8 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX114119
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNDUFS8
Overview
- SupplierGeneTex
- Product NameNDUFS8 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.35 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4728
- Target nameNDUFS8
- Target descriptionNADH:ubiquinone oxidoreductase core subunit S8
- Target synonymsCI-23k; CI23KD; complex I 23kDa subunit; complex I-23kD; MC1DN2; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY
- HostRabbit
- IsotypeIgG
- Protein IDO00217
- Protein NameNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
- Scientific DescriptionThis gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy. Ishiyama A et al., 2017 Oct, Neurol GenetRead more
- Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinsons disease and Parkinsons disease with dementia. Garcia-Esparcia P et al., 2018 Jan, Brain PatholRead more
- Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. Lim SC et al., 2016 Jun, FASEB JRead more