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NDUFS8 antibody

Research Use Only
GTX114119
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNDUFS8
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Overview

  • Supplier
    GeneTex
  • Product Name
    NDUFS8 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.35 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID4728
  • Target name
    NDUFS8
  • Target description
    NADH:ubiquinone oxidoreductase core subunit S8
  • Target synonyms
    CI-23k; CI23KD; complex I 23kDa subunit; complex I-23kD; MC1DN2; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; NADH-ubiquinone oxidoreductase 23 kDa subunit; TYKY
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00217
  • Protein Name
    NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
  • Scientific Description
    This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy. Ishiyama A et al., 2017 Oct, Neurol Genet
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  • Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinsons disease and Parkinsons disease with dementia. Garcia-Esparcia P et al., 2018 Jan, Brain Pathol
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  • Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. Lim SC et al., 2016 Jun, FASEB J
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