Necrostatin-1

MedChem Express

Necrostatin-1 [4311-88-0]

10

4311-88-0

Research Use Only

99.89

C13H13N3OS

259.334

Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC 50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase ( EC 50 =182 nM). Necrostatin-1 is also an IDO inhibitor [1] .

O=C(C(CC1=CNC2=C1C=CC=C2)N3)N(C)C3=S

-20°C,2°C to 8°C

12352200