NEDD4L Polyclonal Antibody

Reddot Biotech

NEDD4L Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.4 mg/ml

Unconjugated

NEDD4L

NEDD4 like E3 ubiquitin protein ligase

NEDD4-2, NEDD4.2, PVNH7, RSP5, hNEDD4-2, E3 ubiquitin-protein ligase NEDD4-like, HECT-type E3 ubiquitin transferase NED4L, neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase, ubiquitin-protein ligase Rsp5

Rabbit

IgG

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.

-20°C

12352203