NF-E2 antibody [N1C3]

GeneTex

NF-E2 antibody [N1C3]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry

Research Use Only

Polyclonal

0.32 mg/ml

Unconjugated

NFE2

nuclear factor, erythroid 2

leucine zipper protein NF-E2; NF-E2; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor, erythroid-derived 2 45 kDa subunit; p45; p45 NF-E2; transcription factor NF-E2 45 kDa subunit

Rabbit

IgG

Transcription factor NF-E2 45 kDa subunit

Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

Human

-20°C or -80°C,2°C to 8°C

12352203