
Western blot of rat cortex lysate showing specific immunolabeling of the ~68kD NF-L protein using GTX82644
NF-L antibody
GTX82644
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityRat
TargetNEFL
Overview
- SupplierGeneTex
- Product NameNF-L antibody
- Delivery Days Customer9
- Application Supplier NoteOptimal working dilutions should be determined experimentally by the end user.
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID4747
- Target nameNEFL
- Target descriptionneurofilament light chain
- Target synonymsCMT1F; CMT2E; CMTDIG; light molecular weight neurofilament protein; neurofilament light polypeptide; neurofilament protein, light chain; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament, light polypeptide 68kDa; NF68; NFL; NF-L; PPP1R110; protein phosphatase 1, regulatory subunit 110
- HostChicken
- IsotypeIgY
- Protein IDP07196
- Protein NameNeurofilament light polypeptide
- Scientific DescriptionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- ReactivityRat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203