Bio-Connect
IHC-P analysis of human diffuse large B cell lymphoma using GTX27970 NFkB p65 antibody.
IHC-P analysis of human diffuse large B cell lymphoma using GTX27970 NFkB p65 antibody.
IHC-P analysis of human diffuse large B cell lymphoma using GTX27970 NFkB p65 antibody.

NFkB p65 antibody

GTX27970
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRELA
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    NFkB p65 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:400 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5970
  • Target name
    RELA
  • Target description
    RELA proto-oncogene, NF-kB subunit
  • Target synonyms
    CMCU; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NFKB3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ04206
  • Protein Name
    Transcription factor p65
  • Scientific Description
    NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Systemic inflammation activates the nuclear factor-kappaB regulatory pathway in adipose tissue. Ekstroem M et al., 2010 Aug, Am J Physiol Endocrinol Metab
    Read more
  • Sustained inflammation due to nuclear factor-kappa B activation in irradiated human arteries. Halle M et al., 2010 Mar 23, J Am Coll Cardiol
    Read more
  • Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstroem macroglobulinemia and does not correlate with p65 NF-kappaB activation. Merzianu M et al., 2006 Jul, Mod Pathol
    Read more