
WB analysis of A431 (A) and HeLa (B) whole cell lysates using GTX27970 NFkB p65 antibody.
NFkB p65 antibody
GTX27970
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRELA
Overview
- SupplierGeneTex
- Product NameNFkB p65 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:400 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- Gene ID5970
- Target nameRELA
- Target descriptionRELA proto-oncogene, NF-kB subunit
- Target synonymsAIF3BL3, CMCU, NFKB3, p65, transcription factor p65, NF-kappa-B p65delta3, NF-kappa-B transcription factor p65, nuclear factor NF-kappa-B p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, v-rel avian reticuloendotheliosis viral oncogene homolog A
- HostRabbit
- IsotypeIgG
- Protein IDQ04206
- Protein NameTranscription factor p65
- Scientific DescriptionNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC41116161
References
- Systemic inflammation activates the nuclear factor-kappaB regulatory pathway in adipose tissue. Ekstroem M et al., 2010 Aug, Am J Physiol Endocrinol MetabRead this paper
- Sustained inflammation due to nuclear factor-kappa B activation in irradiated human arteries. Halle M et al., 2010 Mar 23, J Am Coll CardiolRead this paper
- Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstroem macroglobulinemia and does not correlate with p65 NF-kappaB activation. Merzianu M et al., 2006 Jul, Mod PatholRead this paper





