NFkB p65 (phospho Ser536) antibody
GTX133899
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRELA
Overview
- SupplierGeneTex
- Product NameNFkB p65 (phospho Ser536) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.59 mg/ml
- ConjugateUnconjugated
- Gene ID5970
- Target nameRELA
- Target descriptionRELA proto-oncogene, NF-kB subunit
- Target synonymsAIF3BL3, CMCU, NFKB3, p65, transcription factor p65, NF-kappa-B p65delta3, NF-kappa-B transcription factor p65, nuclear factor NF-kappa-B p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, v-rel avian reticuloendotheliosis viral oncogene homolog A
- HostRabbit
- IsotypeIgG
- Protein IDQ04206
- Protein NameTranscription factor p65
- Scientific DescriptionNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
References
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- Zhang W, Fan Z, Wang F, et al. Tubeimoside I Ameliorates Doxorubicin-Induced Cardiotoxicity by Upregulating SIRT3. Oxid Med Cell Longev. 2023,2023:9966355. doi: 10.1155/2023/9966355Read this paper
- Chou LY, Ho CT, Hung SC. Paracrine Senescence of Mesenchymal Stromal Cells Involves Inflammatory Cytokines and the NF-κB Pathway. Cells. 2022,11(20). doi: 10.3390/cells11203324Read this paper
- Li Y, Wang Z. Interleukin 32 participates in cardiomyocyte-induced oxidative stress, inflammation and apoptosis during hypoxia/reoxygenation via the NOD2/NOX2/MAPK signaling pathway. Exp Ther Med. 2022,24(3):567. doi: 10.3892/etm.2022.11504Read this paper
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- Chang JW, Wu MT, Song WS, et al. Ultrasound Stimulation Suppresses LPS-Induced Proinflammatory Responses by Regulating NF-κB and CREB Activation in Microglial Cells. Cereb Cortex. 2020,30(8):4597-4606. doi: 10.1093/cercor/bhaa062Read this paper
- Chao CC, Lee CW, Chang TM, et al. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). 2020,12(2). doi: 10.3390/cancers12020459Read this paper

![IHC-P analysis of rat spleen tissue section using GTX00947 NFkB p65 antibody [GT1185]. Dilution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX00947/GTX00947_20200327_IHC-P_13_w_23053121_725.webp)