NFYA antibody

GeneTex

NFYA antibody

9

WB: 1:2000-1:10000. IHC-P: 1:400. ELISA: 1:20000-1:100000. EMSA: 2 microL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Polyclonal

Unconjugated

NFYA

nuclear transcription factor Y subunit alpha

CBF-A, CBF-B, HAP2, NF-YA, nuclear transcription factor Y subunit alpha, CAAT-box DNA binding protein subunit A, CCAAT-binding transcription factor subunit B, HAP2 CCAAT-binding protein, NFYA transcript, Transcription factor NF-Y, A subunit, nuclear transcription factor Y subunit A, nuclear transcription factor Y, alpha

Rabbit

IgG

Nuclear transcription factor Y subunit alpha

Nuclear transcription factor Y subunit alpha is a protein that in humans is encoded by the NFYA gene. The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. Anti-NF-Y is ideal for investigators involved in transcription factor research.

-20°C or -80°C,2°C to 8°C

12352203