NHE-1 antibody

GeneTex

NHE-1 antibody

9

WB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SLC9A1

solute carrier family 9 member A1

APNH, LIKNS, NHE-1, NHE1, PPP1R143, sodium/hydrogen exchanger 1, Na(+)/H(+) exchanger 1, Na-Li countertransporter, protein phosphatase 1, regulatory subunit 143, solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive), solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1

Rabbit

IgG

Sodium/hydrogen exchanger 1

The Na+/H+ antiporter (Nhe-1) is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells and is specifically inhibited by the diuretic drug amiloride and activated by a variety of signals including growth factors, mitogens, neurotransmitters, and tumor promoters. Nhe-1 acts as an anchor for actin filaments to control the integrity of the cortical cytoskeleton. This occurs through a previously unrecognized structural link between Nhe-1 and the actin-binding proteins ezrin, radixin, and moesin, collectively referred to as ERM proteins. A structural role for Nhe-1 has been proposed in regulating the cortical cytoskeleton that is independent of its function as an ion exchanger. It is also thought that Nhe-1 play a role in hypertension. At least two isoforms of Nhe-1 are known to exist.

-20°C or -80°C,2°C to 8°C

12352203