Nintedanib

MedChem Express

Nintedanib [656247-17-5]

10

656247-17-5

Research Use Only

99.97

C31H33N5O4

539.62

Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRalpha/beta with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.

O=C1NC2=CC(C(OC)=O)=CC=C2/C1=C(NC3=CC=C(N(C(CN4CCN(C)CC4)=O)C)C=C3)\C5=CC=CC=C5

-20°C,2°C to 8°C

12352200