Nintedanib [656247-17-5]
T1777
CAS Number656247-17-5
Product group Chemicals
Estimated Purity99.85%
Molecular Weight539.62
Overview
- SupplierTargetMol Chemicals
- Product NameNintedanib [656247-17-5]
- Delivery Days Customer4
- CAS Number656247-17-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameNintedanib
- Estimated Purity99.85%
- Molecular FormulaC31H33N5O4
- Molecular Weight539.62
- Scientific DescriptionNintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRalpha, and PDGFRbeta (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis.
- Shelf life instruction3 years
- SMILESCOC(c1cc2c(/C(C(N2)=O)=C(c3ccccc3)/Nc4ccc(N(C(CN5CCN(CC5)C)=O)C)cc4)cc1)=O
- Storage Instruction-20°C
- UNSPSC12352200