Niraparib

MedChem Express

Niraparib [1038915-60-4]

10

1038915-60-4

Research Use Only

99.96

C19H20N4O

320.39

Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3] .

NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O

-20°C,2°C to 8°C

12352200