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Niraparib hydrochloride [1038915-64-8]

Niraparib hydrochloride [1038915-64-8]

T3353
TargetMol Chemicals
CAS Number1038915-64-8
Product group Chemicals
Estimated Purity99.85%
Molecular Weight356.85
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Niraparib hydrochloride
  • Delivery Days Customer
    9
  • CAS Number
    1038915-64-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Niraparib hydrochloride
  • Estimated Purity
    99.85%
  • Molecular Formula
    C19H21ClN4O
  • Molecular Weight
    356.85
  • Scientific Description
    Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. By inhibiting PARP activity, niraparib hydrochloride increases DNA strand breaks, leading to genomic instability and apoptosis. The PARP family of proteins detects and repairs single-strand DNA breaks via the base-excision repair (BER) pathway.
  • Shelf life instruction
    3 years
  • SMILES
    C(N)(=O)C=1C=2C(=CN(N2)C3=CC=C(C=C3)[C@@H]4CCCNC4)C=CC1.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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