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NK1.1 antibody [PK136] (Azide free)

GTX74814
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
TargetKlrb1c
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Overview

  • Supplier
    GeneTex
  • Product Name
    NK1.1 antibody [PK136] (Azide free)
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PK136
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID17059
  • Target name
    Klrb1c
  • Target description
    killer cell lectin-like receptor subfamily B member 1C
  • Target synonyms
    CD161, Klrb1b, Ly-59, Ly55c, Ly59, NK-RP1, NK1.1, NKR-P1.9, NKRP1, NKRP140, Nk-1, Nk-1.2, Nk1, Nk1.2, Nkrp1b, Nkrp1c, ly-55c, killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, NKR-P1 40, NKR-P1B, killer cell lectin-like receptor subfamily A member 1C, lymphocyte antigen 55 complex, locus C, lymphocyte antigen 55c, lymphocyte antigen 59, natural killer cell receptor protein NKR-P1C, natural killer cell receptor-P1, natural killer cell surface protein P1-40, natural killer cell-associated antigen 1
  • Host
    Mouse
  • Isotype
    IgG2a
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Combined alpha-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma. Lin X et al., 2019, Cancer Biol Ther
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  • Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells. Mukherjee S et al., 2018 Jul 25, J Exp Clin Cancer Res
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  • Lyn-dependent signaling regulates the innate immune response by controlling dendritic cell activation of NK cells. Krebs DL et al., 2012 May 15, J Immunol
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  • Type I interferon is selectively required by dendritic cells for immune rejection of tumors. Diamond MS et al., 2011 Sep 26, J Exp Med
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  • The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo. Lubinski JM et al., 2011 Apr, J Virol
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  • Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes. Awasthi A et al., 2010 Aug 30, J Exp Med
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  • Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Coudert JD et al., 2008 Apr 1, Blood
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  • Functional requirements for signaling through the stimulatory and inhibitory mouse NKR-P1 (CD161) NK cell receptors. Ljutic B et al., 2005 Apr 15, J Immunol
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  • Effects of survivin antagonists on growth of established tumors and B7-1 immunogene therapy. Kanwar JR et al., 2001 Oct 17, J Natl Cancer Inst
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