
Immunofluorescence analysis of methanol-fixed HeLa, using KLRC1(GTX108498) antibody at 1:200 dilution.
NKG2A antibody [N1N2], N-term
GTX108498
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetKLRC1
Overview
- SupplierGeneTex
- Product NameNKG2A antibody [N1N2], N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.1 mg/ml
- ConjugateUnconjugated
- Gene ID3821
- Target nameKLRC1
- Target descriptionkiller cell lectin like receptor C1
- Target synonymsCD159A, NKG2, NKG2A, NKG2-A/NKG2-B type II integral membrane protein, C-lectin type II protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-1/B activating NK receptor, NKG2-A/B type II integral membrane protein, NKG2-A/B-activating NK receptor, killer cell lectin-like receptor subfamily C, member 1, natural killer cell lectin, natural killer group protein 2
- HostRabbit
- IsotypeIgG
- Protein IDP26715
- Protein NameNKG2-A/NKG2-B type II integral membrane protein
- Scientific DescriptionNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![KLRC1 antibody [N1N2], N-term detects KLRC1 protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. KLRC1 antibody [N1N2], N-term (GTX108498) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min KLRC1 antibody [N1N2], N-term detects KLRC1 protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. KLRC1 antibody [N1N2], N-term (GTX108498) dilution: 1:500.
Antigen Retrieval: Trilogy? (EDTA based, pH 8.0) buffer, 15min](https://www.genetex.com/upload/website/prouct_img/normal/GTX108498/GTX108498_39862_IHC_w_23060120_176.webp)
![Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with NKG2A antibody [N1N2], N-term (GTX108498) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with NKG2A antibody [N1N2], N-term (GTX108498) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX108498/GTX108498_44111_20230929_WB_B_23101921_416.webp)





![Whole cell extract (30 μg) was separated by 12% SDS-PAGE, and the membrane was blotted with NKG2A antibody [HL2718] (GTX639545) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639545/GTX639545_45383_20240503_WB_24050701_313.webp)

