
Western Blot Positive WB detected in: HepG2 whole cell lysate, U251 whole cell lysate, U87 whole cell lysate All lanes: TTF1 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa
NKX2-1 Recombinant Monoclonal Antibody
CSB-RA181189A0HU
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetNKX2-1
Overview
- SupplierCusabio
- Product NameNKX2-1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID6C11
- ConjugateUnconjugated
- Gene ID7080
- Target nameNKX2-1
- Target descriptionNK2 homeobox 1
- Target synonymsBCH; BHC; homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK-2 homolog A; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; thyroid nuclear factor 1; thyroid transcription factor 1; thyroid-specific enhancer-binding protein; TITF1; TTF1; TTF-1
- IsotypeIgG
- Protein IDP43699
- Protein NameHomeobox protein Nkx-2.1
- Scientific DescriptionTranscription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203