NKX2.1 antibody [NX2.1/690]

GeneTex

NKX2.1 antibody [NX2.1/690]

9

ICC/IF: 1-2microg/ml. IHC-P: 1-2microg/ml for 30 minutes at RT. FACS: 1-2microg/106 cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

NX2.1/690

0.2 mg/ml

Unconjugated

NKX2-1

NK2 homeobox 1

BCH; BHC; homeobox protein NK-2 homolog A; homeobox protein Nkx-2.1; NK-2; NK-2 homolog A; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; thyroid nuclear factor 1; thyroid transcription factor 1; thyroid-specific enhancer-binding protein; TITF1; TTF1; TTF-1

Mouse

IgG1

Homeobox protein Nkx-2.1

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias TTF1 with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203