
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti Cryopyrin/CIAS1/NALP3 Polyclonal Antibody, Unconjugated (bs-10021R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
NALP3/CIAS1 Polyclonal Antibody
BS-10021R
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat
TargetNLRP3
Overview
- SupplierBioss
- Product NameNALP3/CIAS1 Polyclonal Antibody
- Delivery Days Customer16
- ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- Applications SupplierWB(WB=1:500-2000), IHC-P(IHC-P=1:100-500), IHC-F(IHC-F=1:100-500), IF(IHC-P)(IF=1:100-500), IF()
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID114548
- Target nameNLRP3
- Target descriptionNLR family pyrin domain containing 3
- Target synonymsAGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCAS1, FCU, KEFH, MWS, NALP3, PYPAF1, NACHT, LRR and PYD domains-containing protein 3, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, NACHT, LRR and PYD containing protein 3, PYRIN-containing APAF1-like protein 1, caterpiller protein 1.1, cold autoinflammatory syndrome 1 protein, cold-induced autoinflammatory syndrome 1 protein, cryopyrin, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, deafness, autosomal dominant 34, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
- HostRabbit
- IsotypeIgG
- Protein IDQ96P20
- Protein NameNACHT, LRR and PYD domains-containing protein 3
- ReactivityCanine, Human, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC41116161
References
- A selected small molecule prevents inflammatory osteolysis through restraining osteoclastogenesis by modulating PTEN activity. Chen Y et al., 2020 Dec, Clin Transl MedRead this paper
- Estrogen deficiency aggravates apical periodontitis by regulating NLRP3/caspase-1/IL-1beta axis. Guan X et al., 2020, Am J Transl ResRead this paper
- HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2. Yang X et al., 2020 Jun, Int ImmunopharmacolRead this paper
- Exposure of DBP in gestation induces inflammation of testicular Sertoli cells in progeny by activating NLRP3 inflammasomes. Zhou Y et al., 2020 Mar 10, Sci Total EnvironRead this paper
- XingNaoJing injections protect against cerebral ischemia/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression. Qu XY et al., 2019 Jul, Chin J Nat MedRead this paper
- Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation in mice. Chen Y et al., 2019 Oct, Biomed PharmacotherRead this paper
- The protective effect of oleanolic acid on NMDA-induced MLE-12 cells apoptosis and lung injury in mice by activating SIRT1 and reducing NF-kappaB acetylation. Peng XP et al., 2019 May, Int ImmunopharmacolRead this paper
- Harmine mitigates LPS-induced acute kidney injury through inhibition of the TLR4-NF-kappaB/NLRP3 inflammasome signalling pathway in mice. Niu X et al., 2019 Apr 15, Eur J PharmacolRead this paper
- NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media. Kariya S et al., 2018 Dec, Acta OtolaryngolRead this paper
- Autophagy inhibition-enhanced assembly of the NLRP3 inflammasome is associated with cisplatin-induced acute injury to the liver and kidneys in rats. Qu X et al., 2018 Oct 6, J Biochem Mol ToxicolRead this paper















![Boiled and unboiled THP-1 whole cell and membrane extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with NLRP3 antibody [C3], C-term (GTX106313) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. (WCE: whole cell extract; ME: membrane extract)](https://www.genetex.com/upload/website/prouct_img/normal/GTX106313/GTX106313_44454_20211008_WB_Fraction_w_23060120_958.webp)