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NLRP7 antibody [N3C2], Internal

GTX120931
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Sheep
TargetNLRP7
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Overview

  • Supplier
    GeneTex
  • Product Name
    NLRP7 antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.76 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID199713
  • Target name
    NLRP7
  • Target description
    NLR family pyrin domain containing 7
  • Target synonyms
    CLR19.4, HYDM, NALP7, NOD12, PAN7, PYPAF3, NACHT, LRR and PYD domains-containing protein 7, NACHT, LRR and PYD containing protein 7, NACHT, leucine rich repeat and PYD containing 7, PYRIN-containing Apaf1-like protein 3, nucleotide-binding oligomerization domain protein 12, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8WX94
  • Protein Name
    NACHT, LRR and PYD domains-containing protein 7
  • Scientific Description
    This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human, Sheep
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Li G, Tian X, Lv D, et al. NLRP7 is expressed in the ovine ovary and associated with in vitro pre-implantation embryo development. Reproduction. 2019,158(5):415-427. doi: 10.1530/REP-19-0081
    Read this paper
  • Akoury E, Zhang L, Ao A, et al. NLRP7 and KHDC3L, the two maternal-effect proteins responsible for recurrent hydatidiform moles, co-localize to the oocyte cytoskeleton. Hum Reprod. 2015,30(1):159-69. doi: 10.1093/humrep/deu291
    Read this paper